Imagine knowing everything, every possible fact in the world, but not knowing you you were. You understand the entire world around you, but have no idea where you came from. Every sight is monochromatic, but seemingly insignifcant people and items are in color, leading clues to your identity. That's the life of John Doe.
A sleeper (hit?) from early 2000 FOX, John Doe is the story of a man who finds himself buck naked on an island off the coast of Seattle. He sees everything in black and white, has no memory of who he is, but knows everything else imaginable. The entire series unravels the mystery that led him to his situation.
John Doe stars Domic Purcell, a FOX regular more known for his role in Prison Break (before he got ripped) as the titular character who solves crimes with his knowledge of, well, everything. Imagine Sherlock Holmes with the entire knowledge of the encyclopedia. John is joined by two members of the Seattle PD, his new bartender friend and the local artist/waitress. It doesn't really sound like a team of crime fighters and the actual crime fighting was convoluted. John's vision clues are not relevant to why he's color blind and the knowledge that he uses to solve mysteries just seem useless. But the series is somehow compelling. I like it.
This is truly one of FOX's greatest mystery shows in recent years. Unfortunately, the series was canceled prematurely at a cliffhanger that revealed the shocking identity of the villain. The creators later revealed would-be secrets, ensuring that there be no reason to ever revisit the series in any way. There's no known DVD release, meaning that it's going to be hard to find.